Trends in Randomized Controlled Trials in Anesthesia

By November 9, 2018Uncategorized

The primary objective of an anesthesiologist is to ensure that the patient undergoes a safe, effective procedure with an optimized post-operative recovery time. In order to effectively deliver on this, it is essential for anesthesia providers to be cognizant of changes in the field, whether that be in the form of new iterations of delivery methods or novel medications used in the operating room (OR). Randomized controlled trials (RCTs) are utilized to compare the efficacy of medical technologies and to assess their practical applications in the clinical setting. In the field of anesthesia management, administrators and physicians alike should remain informed about relevant research developments.

At the Joint World Congress on Regional Anesthesia held in April 2018, a team of anesthesiologist-researchers presented an analysis of the field’s scientific literature spanning over a century[1]. Utilizing a series of standardized metrics, the research team sought to measure bias, reliability, and access in anesthesiology-related RCT literature over time. They found that the summarized risk of bias decreased over time while the sample size of patients included in these trials effectively remained the same. These findings suggest that while the strategic underpinnings of anesthesia trials are becoming quantitatively less biased, the access to patient participants has remained the same despite the recent increase in clinical trials conducted globally[2]. This is an important consideration for healthcare management, particularly those in the service delivery lines as they consider introducing novel medications and delivery mechanisms to the existing hospital framework. Healthcar